I can across this on RapaNews and tried it out tonight. Worked really well. I usually take 50-100 mg acarbose with meals, but tried this cocktail instead. I even had some cake bc it was my wife's birthday. Greatly blunted the glucose increase. Thank you for posting this!!
Have you tried acarbose with fruit (especially apples vs stone fruits vs tropical fruits)? Stone and Tropical fruits have more sugars in the form of disaccharides... Have you figured out how to reduce the glucose spike from fruit high in monosaccharide sugars?
Hi Alex, Great question! I was focusing on inhibiting the breakdown of starches into monosaccharides, so most of these won't do a whole lot for the monosaccharides themselves, but there are some other strategies that could work well here.
Some compounds can inhibit the transporters in the gut that take up glucose (i.e., SGLT1). Allulose does this weakly, and there are pharma options (e.g., phlorizin, sotagliflozin) that can do this very effectively. The pharma options also lower overall glucose levels via kidney excretion and are some of my favorite longevity drugs.
Finally, there are also some probiotics that are intended to convert glucose and fructose into mannitol, which is poorly absorbed. I'm less familiar with these, but they could be worth exploring.
I can across this on RapaNews and tried it out tonight. Worked really well. I usually take 50-100 mg acarbose with meals, but tried this cocktail instead. I even had some cake bc it was my wife's birthday. Greatly blunted the glucose increase. Thank you for posting this!!
Thanks for sharing, Daniel! So glad it is working for you. And yes, this is a great way to feel better about cake ;)
Have you tried acarbose with fruit (especially apples vs stone fruits vs tropical fruits)? Stone and Tropical fruits have more sugars in the form of disaccharides... Have you figured out how to reduce the glucose spike from fruit high in monosaccharide sugars?
Hi Alex, Great question! I was focusing on inhibiting the breakdown of starches into monosaccharides, so most of these won't do a whole lot for the monosaccharides themselves, but there are some other strategies that could work well here.
Some compounds can inhibit the transporters in the gut that take up glucose (i.e., SGLT1). Allulose does this weakly, and there are pharma options (e.g., phlorizin, sotagliflozin) that can do this very effectively. The pharma options also lower overall glucose levels via kidney excretion and are some of my favorite longevity drugs.
Finally, there are also some probiotics that are intended to convert glucose and fructose into mannitol, which is poorly absorbed. I'm less familiar with these, but they could be worth exploring.